Advanced Glycation End Products (AGEs) and their role in aging and age-related disease
Advanced Glycation Endproducts (AGEs) are a family of compounds resulting from a series of non-enzymatic reactions between proteins, lipids, or nucleic acids, and sugars. The initial step, known as glycation, involves the binding of a sugar molecule to an amino group and is reversible. However, as the glycated compound undergoes subsequent reactions, culminating in the […]
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