elder eating vegetables to limit Advanced Glycation Endproduct intake through diet

Advanced Glycation End Products (AGEs) and their role in aging and age-related disease

Advanced Glycation Endproducts (AGEs) are a family of compounds resulting from a series of non-enzymatic reactions between proteins, lipids, or nucleic acids, and sugars. The initial step, known as glycation, involves the binding of a sugar molecule to an amino group and is reversible. However, as the glycated compound undergoes subsequent reactions, culminating in the

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cell releasing molecules in the sourrounding environment

Senescent Cells and SASP in Aging and Longevity Medicine

In the longevity medicine field, one of the spotlights is being cast on cells that reach an important stage in life, specifically, senescent cells. When cells are stressed, depending on the cell, type of stressor and intensity of the stimulus, they can respond by inducing repair processes, inducing cell death, or inducing senescence. These senescent

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hallmarks of health

What are the 8 Hallmarks of Health?

Health is often defined simply as the absence of disease. However, in this article, we will delve into a more nuanced understanding of health. Here, health is not merely the lack of something negative, but rather, it is characterized by a series of dynamic features that actively maintain a state of well-being and stave off

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biological age vs chronological age

Chronological age, biological age and deep aging clocks

Aging is a very complex biological phenomenon characterized by a gradual decline in physiological function, accumulation of damage, the development of age-related diseases, increased frailty and susceptibility to infections and eventually death. Genetics, environmental factors and lifestyle factors all influence the aging process, the lifespan and healthspan. What is chronological age? Chronological age is defined

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hallmarks of aging

Why do we age? The Hallmarks of aging in longevity medicine (2023)

In 2013, Lopez-Otin et al. proposed the original nine hallmarks of aging in an article published in Cell. Since then, the field of longevity medicine has witnessed significant growth, with new research and studies enhancing our understanding of the cellular and molecular mechanisms involved in the aging process. In 2022, a panel of experts reviewed

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representation of aging process and stages of aging with matches being increasingly left to burn out.

The Evolution of Aging Theories in longevity medicine

Over the past few decades, scientists have proposed several theories to explain the process of aging. As our understanding of biology and related fields has grown, we have abandoned or modified some of these theories to fit our current knowledge. However, some of these outdated theories still hold significant influence on the general public and

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word cloud longevity medicine glossary

A Comprehensive Glossary of Longevity Medicine: Explaining the Jargon

Longevity medicine is an exciting and rapidly advancing field that aims to extend healthy human lifespan. However, the sheer volume of scientific terms and jargon used in longevity research can be overwhelming, especially for those who are new to the field. In this comprehensive glossary, I’ll briefly explain some of the most commonly used terms

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longevity medicine

Introduction to longevity medicine and healthy lifespan extension

Imagine living to be 100 years old, but with the vitality and health of someone half your age. This is no longer a far-fetched dream, but a real possibility with the rapidly emerging field of longevity medicine. What is longevity medicine? Longevity medicine is a rapidly growing field of research focused on extending healthy lifespan

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acne scar on face

How to make acne scars disappear? Overview of treatment options

Acne scars are a common aesthetic issue because acne is one of the most prevalent skin diseases worldwide, affecting around 85% of adolescents and young adults of all ethnicities. When an inflammatory acne lesion heals, it typically leaves a visible mark in almost 100% of cases. The more severe the inflammation, the more disfiguring the

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